New Products Listed in the First Half of 2011: Chromatography

Chromatography is one of the most widely used analytical instruments in the world. In recent years, life science research, drug development, and food safety testing have become important drivers for the growth of the chromatograph market.

For more details of various products, see the following categories, ranking in no particular order.

First, the gas chromatograph gas chromatograph technology After years of development, the technology is very mature, and there are fewer new products. In the first half of 2011, Thermo Fisher introduced the new miniature gas chromatograph C2V-200 at Pittcon. The core technology of the instrument is to have a unique separation column with only a credit card size, which includes an injection system and columns. And detector, C2V-200 can be applied to the rapid analysis of natural gas.

Agilent introduced the Agilent LTM-II system, which uses a patented second-generation, low-heat-capacity patented technology. The column is enveloped by a heating element and a temperature sensor. Both the rate of temperature increase and the rate of temperature decrease will be significantly faster, resulting in faster chromatographic performance. cycle. The system can be installed on the Agilent 7890A GC. In addition, Agilent launched Crossscale, a consumable product for the current generation of gas chromatographs for various brands and models, at this year's Pittcon. Agilent hopes that “users can enjoy Agilent Technologies and products on different brands of gas chromatographs, and One-stop shopping for the laboratory."

Second, UHPLC/UPLC

In terms of liquid chromatography, UHPLC/UPLC has become the main direction for the development of liquid chromatography. In recent years, companies have introduced UHPLC-related products every year. The mainstream manufacturers of liquid chromatographs on the market also have UHPLC products, and the market tends to be flat. In the first half of this year, only Rambo Chromatography launched a UHPLC UP2000 with a maximum withstand voltage of 25,000 psi.

Agilent introduced this year's Pittcon with ISET, a method conversion software for the Agilent 1290 Infinity LC system, which can convert UHPLC methods to HPLC methods and can be converted to different brands of HPLC systems.

As the UPLC technology's first commercialized company, Waters, has made new developments on the UPLC platform. In the first half of this year, Waters introduced the ACQUITY UPLC System based on two-dimensional chromatographic technology and the UPLC-based ACQUITY UPSFCTM System. Waters' expansion of two-dimensional chromatographic technology on the proven ACQUITY UPLC technology allows scientists to better perform sample trapping, center distillate and parallel column regeneration to eliminate matrix effects, which can satisfy "some of the most demanding requirements for ultra-high sensitivity. Challenging experiments while maintaining excellent instrument durability and instrument uptime.”

The ACQUITY UPSFCTM system allows scientists to use carbon dioxide as the primary mobile phase for normal phase separation, replacing expensive and toxic solvents, which can save the lab thousands of dollars and extend the life of the instrument. Compared with traditional HPLC, it can make the research or quality control laboratories of many industries gain huge benefits in the routine UPSFC separation.

In addition, Thermo Fisher Scientific launched the nano-upgraded UHPLC EASY-nLC 1000. The advanced design of the system increases the recognition rate of proteins and peptides by higher pressure and changes in bead size and column length. %, ideal for separating biomolecules.

Third, HPLC

In the area of ​​general-purpose HPLC, Hitachi High-Tech has launched a new generation of new-generation liquid Chromaster this year. This product has undergone global research and is unique in terms of technology. It is characterized by its performance, ease of operation, and durability of the instrument. There is a great improvement. For example, the pump uses a new low-pressure gradient system high-frequency mode HFM. Compared to the traditional method, the HFM solenoid valve switching frequency is doubled and solvent mixing efficiency is improved. The autosampler designed a new syringe drive unit. Direct connection of the injection port and injection valve completely eliminates the dead volume of the autosampler flow path, and actively cleans the outer wall of the injection needle through a dedicated pump, achieving extremely low sample residue.

A Liquid Chromatograph LC-10Tvp HPLC developed jointly by Scitech and Syltech of the United States, which fully realizes man-machine dialogue and remote unmanned operation.

Fourth, the column in the column, the existing gas chromatography column can solve 99% of the application problems, the corresponding new products are also less; and UHPLC popularity, the corresponding column types are far less than ordinary HPLC Columns, major manufacturers are concerned about the R&D of UHPLC columns, and more new products are introduced.

In the first half of 2011, Agilent introduced the ZORBAX RRHD 300SB-C18 1.8 μm column for UHPLC systems, which is a reversed-phase silica gel column that enables reversed-phase chromatographic characterization of higher-order structures of intact proteins and protein hydrolysates; Thermo Fisher has introduced the Accucore HPLC series of columns based on the state-of-the-art superficial porous solid core enhancement technology combined with extensive experience in phase bonding and column packing to provide sub 2μm packing efficiency while the column pressure is in ordinary HPLC. The range of chromatographs that can be tolerated, and the overall increase in laboratory work flow and efficiency; Shiseido launched CAPCELL PAK C18 MGIII-H, which combines high separation capacity and high pressure resistance.

Regarding the declared new products, any "instrument manufacturers on the Internet" can apply for the latest listed instruments at any time. All new products that have been approved and passed will be made available in the Instrument Information Network "new products column", "online instrument exhibition", "information information network homepage", etc. Multi-faceted display; some new products with complete application materials and special features will also be recommended for publication in the "Instrumental News" magazine; the sooner you declare new products, you will get more display opportunities.