Synthetic biology will be industrialized
According to China Daily drying Reuters Web of Science recently reported that British scientists have developed a new method, a new component factory microbial production time can be reduced from two days to six hours. The researchers believe that this is a step closer to the new industrial revolution. They can mass-produce components for bio-plants and promote the practical application of synthetic biology, which includes providing patients with better methods of administration and improving the mining of minerals from deep underground. Production, promotion of biofuel production, etc.
The research team headed by Prof. Paul Fremont, co-director of the Institute of Synthetic Biology and Innovation at Imperial College, published a paper in the Journal of Nucleic Acid Research on February 1 stating that most products were handmade before the industrial revolution and thus produced Inefficient, expensive, and limited production. The field of synthetic biology is currently at a similar critical period, and each component must be tested and made from zero, which takes a long time. The new method can greatly speed up the production and testing of biological components.
Scientists use DNA to make components and inject them into carrier cells to build biological factories. However, one of the major obstacles encountered in the current development of synthetic biology is the lack of components for constructing various new biofactories. Existing methods of manufacturing components are time consuming. Scientists must reconstitute DNA in cells and observe whether they work properly. The methods designed by the Fremont team do not require the reorganization of DNA, they can use off-the-shelf components to build large new laboratories, and build more advanced biofactories accordingly.
The center’s James Chapel said: “One of the main goals of synthetic biology is to discover a new process that can be industrialized and mass produce a variety of biological factories, which helps to unleash the potential of synthetic biology. Better for the benefit of society. We provide a quick way to develop new components and move closer to this goal.â€
The recombined DNA encodes a message that is passed to the cell's production plant, the ribosome, via messenger RNA (mRNA). Ribosomes translate genetic information into instructions that direct the cells to function. For the first time, the researchers confirmed that this method can also be successful in vitro in vitro.
The advantage of recombining DNA in vitro is that scientists can develop cell-like environments while testing multiple recombinant DNAs to speed up the assembly process. The next stage of research is to increase the type and design of the components needed for this method. In addition, scientists plan to develop a method that uses robots to automate the entire process.
Professor Richard Kartney, another co-director of the Institute of Synthetic Biology and Innovation at Imperial College, points out that the British government believes that synthetic biology has the potential to create new industries and employment opportunities. The center is implementing a number of industries. The department developed a research plan for applied technology. The above research results are only part of the plan.
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